BDBM50417842 CHEMBL1667965

SMILES C(N1CCC[C@@H](C1)Oc1ccc2cnccc2c1)c1ccccc1

InChI Key InChIKey=AKUKFSSRYRAGER-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50417842   

TargetRho-associated protein kinase 2(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417842(CHEMBL1667965)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417842(CHEMBL1667965)
Affinity DataIC50: 170nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50417842(CHEMBL1667965)
Affinity DataIC50: 331nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed