BDBM50418849 CHEMBL1738840

SMILES COc1ccnc(CCc2nc3ncccc3[nH]2)c1

InChI Key InChIKey=YBOCDKFRGBOOFO-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50418849   

TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50: 81.3nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human nNOS transfected in baculovirus infected Sf9 cells assessed as reduction of [3H]L-arginine conversion to [3H]L-citrulline by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of human eNOS transfected in baculovirus infected Sf9 cells assessed as reduction of [3H]L-arginine conversion to [3H]L-citrulline by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50: 86nMAssay Description:Inhibition of human iNOS transfected in baculovirus infected Sf9 cells assessed as reduction of [3H]L-arginine conversion to [3H]L-citrulline by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed