BDBM50419755 CHEMBL1949911

SMILES C1CN(CCO1)c1nc(nc2sccc12)-c1cccc2[nH]ncc12

InChI Key InChIKey=JFOPZQXMAMQTAU-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419755   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50419755(CHEMBL1949911)Copy SMILESCopy InChI

Affinity DataKi:  47nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50419755(CHEMBL1949911)Copy SMILESCopy InChI

Affinity DataKi:  1.17E+3nMAssay Description:Apparent binding affinity to PI3Kbeta using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL