BDBM50420273 CHEMBL2089208

SMILES COC(=O)C(N1C(c2ccc(Cl)cc2)C(=S)Nc2ccc(F)cc2C1=O)c1ccc(Cl)cc1

InChI Key InChIKey=VTEPOEPLGVFUFO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420273   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420273(CHEMBL2089208)
Affinity DataKi:  89nMAssay Description:Inhibition of MDM2 binding domain assessed as inhibition of p53 binding to MDM2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420273(CHEMBL2089208)
Affinity DataKi:  89nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed