BDBM50420608 CHEMBL2087453

SMILES COc1ccc(cc1)-c1cc(NC(=O)CCCCN2CCOCC2)[nH]n1

InChI Key InChIKey=RPLWNHKGFXWLSL-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50420608   

TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420608(CHEMBL2087453)
Affinity DataIC50: 1.16E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420608(CHEMBL2087453)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420608(CHEMBL2087453)
Affinity DataEC50:  590nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed