BDBM50420978 8-Phenoxymethylcaffeine (8a)::CHEMBL2088299

SMILES Cn1c(COc2ccccc2)nc2n(C)c(=O)n(C)c(=O)c12

InChI Key InChIKey=ZMYAPXMDMKEKHX-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50420978   

TargetAdenosine receptor A2a(Rat)
North-West University, Private Bag X6001, Potchefstroom 2520, South Africa

LigandPNGBDBM50420978(CHEMBL2088299 | 8-Phenoxymethylcaffeine (8a))
Affinity DataKi:  137nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
North-West University, Private Bag X6001, Potchefstroom 2520, South Africa

LigandPNGBDBM50420978(CHEMBL2088299 | 8-Phenoxymethylcaffeine (8a))
Affinity DataKi:  2.37E+3nMAssay Description:Displacement of [3H]-NECA from Adenosine A2A receptor in Sprague-Dawley rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM50420978(CHEMBL2088299 | 8-Phenoxymethylcaffeine (8a))
Affinity DataKi:  3.09E+3nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat whole brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM50420978(CHEMBL2088299 | 8-Phenoxymethylcaffeine (8a))
Affinity DataKi:  4.01E+3nMAssay Description:Displacement of [3H]DPCPX from adenosine receptor A1 in rat brain membrane in presence of GTP by GTP shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50420978(CHEMBL2088299 | 8-Phenoxymethylcaffeine (8a))
Affinity DataIC50: 5.78E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected insect cells using kynuramine as substrate after 20 mins by horseradish perox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50420978(CHEMBL2088299 | 8-Phenoxymethylcaffeine (8a))
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected insect cells using kynuramine as substrate after 20 mins by horseradish perox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed