BDBM50421606 CHEMBL337188

SMILES CN(C)C(=O)c1ccc(CCC(COc2ccc(cc2)-c2cccc(c2)[N+]([O-])=O)n2c(O)csc2=O)cc1

InChI Key InChIKey=QFHREYXLYNYTFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50421606   

TargetP2X purinoceptor 7(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421606(CHEMBL337188)
Affinity DataIC50: 158nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed