BDBM50421701 CHEMBL5287448

SMILES CNC(=O)c1cc(CNC(=O)c2ccc3n(cc(COc4ccc5[nH]ccc5c4)c3c2)S(C)(=O)=O)cc(=O)[nH]1

InChI Key InChIKey=VRQGZVGFCPUFBJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50421701   

TargetSentrin-specific protease 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50421701(CHEMBL5287448)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of human recombinant SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO1-AMC as substrate incubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50421701(CHEMBL5287448)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human recombinant His6 tagged SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO1-AMC as substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50421701(CHEMBL5287448)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant His6 tagged SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO2-AMC as substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50421701(CHEMBL5287448)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant His6 tagged SENP1 catalytic domain expressed in Escherichia coli BL21 (DE3) using SUMO3-AMC as substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed