BDBM50422409 CHEMBL347582

SMILES C[C@H](CNc1cccc(CC(=O)NS(=O)(=O)c2ccc(C)cc2)c1)NC[C@H](O)c1cccc(Cl)c1

InChI Key InChIKey=NKVSVXNFJOOTMR-UHFFFAOYSA-N

Data  2 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50422409   

TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422409(CHEMBL347582)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422409(CHEMBL347582)
Affinity DataEC50:  6.30nMAssay Description:Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422409(CHEMBL347582)
Affinity DataEC50: <5.01E+3nMAssay Description:Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422409(CHEMBL347582)
Affinity DataEC50:  6.30nMAssay Description:Ability to cause cAMP accumulation in CHO cells expressing human beta-3 AR expressed as the negative logarithm of the molar drug concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422409(CHEMBL347582)
Affinity DataEC50: <1.00E+3nMAssay Description:Concentration that causes 50% inhibition of human beta 2 adrenergic receptor (AR), expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422409(CHEMBL347582)
Affinity DataEC50: <5.01E+3nMAssay Description:Concentration that causes 50% inhibition of human beta 1 adrenergic receptor (AR), expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422409(CHEMBL347582)
Affinity DataIC50: 1.58E+4nMAssay Description:Receptor binding assay(Beta-2 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422409(CHEMBL347582)
Affinity DataIC50: 5.01E+3nMAssay Description:Receptor binding assay(Beta-1 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed