BDBM50424536 CHEMBL2312143

SMILES COc1ccc(cc1-c1ccnc(Nc2ccc(cc2)N2CCN(C)CC2)c1)C#N

InChI Key InChIKey=QABZWIZUOWNALE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424536   

TargetTRAF2 and NCK-interacting protein kinase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424536(CHEMBL2312143)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TNIK-mediated TCF4/beta-casein transcription in human HCT116 cells by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424536(CHEMBL2312143)
Affinity DataIC50: 5nMAssay Description:Inhibition of TNIK (unknown origin) by ADP glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed