BDBM50424720 CHEMBL2314511

SMILES Cc1cccc2c(c([nH]c12)C(O)=O)-c1ccccc1

InChI Key InChIKey=OSOLISRTJWBBIW-UHFFFAOYSA-N

Data  3 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50424720   

TargetReplication protein A 70 kDa DNA-binding subunit(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50424720(CHEMBL2314511)
Affinity DataKd:  6.40E+5nMAssay Description:Binding affinity to RPA70N (1 to 120) site1 (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50424720(CHEMBL2314511)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of FITC-AHx-GQVGRQLAIIGDDINR-NH2 from Bcl2 (unknown origin) after 1 hr by fluorescence polarization anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50424720(CHEMBL2314511)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of FITC-AHx-GQVGRQLAIIGDDINR-NH2 from Bcl-xL (unknown origin) after 1 hr by fluorescence polarization anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50424720(CHEMBL2314511)
Affinity DataKi:  1.36E+5nMAssay Description:Displacement of FITC-AHx-KALETLRRVGDGVQRNHETAF-NH2 from human MCl1 (172 to 327) expressed in Escherichia coli BL21 (DE3) after 1 hr by fluorescence p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed