BDBM50425968 CHEMBL2314388

SMILES Oc1c(OS([O-])(=O)=O)cc(cc1OS([O-])(=O)=O)C(=O)OC[C@H]1O[C@@H](OC(=O)c2cc(OS([O-])(=O)=O)c(O)c(OS([O-])(=O)=O)c2)[C@H](OC(=O)c2cc(OS([O-])(=O)=O)c(O)c(OS([O-])(=O)=O)c2)[C@@H](OC(=O)c2cc(OS([O-])(=O)=O)c(O)c(OS([O-])(=O)=O)c2)[C@@H]1OC(=O)c1cc(OS([O-])(=O)=O)c(O)c(OS([O-])(=O)=O)c1

InChI Key InChIKey=MLAFGGAKHVUBGK-UHFFFAOYSA-D

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425968   

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50425968(CHEMBL2314388)
Affinity DataIC50: 551nMAssay Description:Inhibition of human FXIa assessed as S-2366 hydrolysis after 10 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50425968(CHEMBL2314388)
Affinity DataIC50: 40nMAssay Description:Inhibition of human neutrophil elastase using S1384 as substrate preincubated for 5 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed