BDBM50426366 CHEMBL2326408

SMILES COc1cc(O)c(C(CC(=O)N2C[C@@H](C)C[C@@H](C)C2)c2ccc3OCOc3c2)c(OC)c1

InChI Key InChIKey=YEKVAIMYYCZDLI-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50426366   

TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50: 51nMAssay Description:Displacement of fluorescein-labeled 25-hydroxycholesterol from human RORgammat LBD (262-518) Escherichia coli BL21(DE3) after 6 hrs by fluorescence p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50: 51nMAssay Description:Displacement of fluorescein-labeled 25-hydroxycholesterol from human RORgammat LBD (262-518) Escherichia coli BL21(DE3) after 6 hrs by fluorescence p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in HEK293t cells co-expressing Gal4-DNA binding domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
New York University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at TRbeta (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
New York University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50: 4.50E+3nMAssay Description:Antagonist activity at TRalpha (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
New York University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at LXRalpha (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
New York University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50: 1.40E+4nMAssay Description:Antagonist activity at ERRalpha (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed