BDBM50426395 CHEMBL2326713

SMILES CNc1nc(Nc2cn(C)nc2C)ncc1C(F)(F)F

InChI Key InChIKey=UTBRMMZZLJGOHJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50426395   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Genentech

Curated by ChEMBL

LigandBDBM50426395(CHEMBL2326713)Copy SMILESCopy InChI

Affinity DataIC50: 52nMAssay Description:Inhibition of LRRK2 (unknown origin) autophosphorylation by cell-based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
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TargetCytochrome P450 1A2(Human)
Genentech

Curated by ChEMBL

LigandBDBM50426395(CHEMBL2326713)Copy SMILESCopy InChI

Affinity DataIC50: 700nMAssay Description:Reversible inhibition of CYP1A2 (unknown origin) using phenacetin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL