BDBM50426401 CHEMBL2326715

SMILES CNc1nc(Nc2cnn(C)c2Cl)ncc1C(F)(F)F

InChI Key InChIKey=QSRNIRWKKRHBNL-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50426401   

TargetCytochrome P450 1A2(Human)
Genentech

Curated by ChEMBL

LigandBDBM50426401(CHEMBL2326715)Copy SMILESCopy InChI

Affinity DataIC50: 5.80E+3nMAssay Description:Reversible inhibition of CYP1A2 (unknown origin) using phenacetin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Genentech

Curated by ChEMBL

LigandBDBM50426401(CHEMBL2326715)Copy SMILESCopy InChI

Affinity DataIC50: 39nMAssay Description:Inhibition of LRRK2 (unknown origin) autophosphorylation by cell-based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL