BDBM50426403 CHEMBL2326726

SMILES CNc1nc(Nc2cnn(CC(C)(C)O)c2Cl)ncc1C(F)(F)F

InChI Key InChIKey=IKBCWJODRQLGHR-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50426403   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50426403(CHEMBL2326726)
Affinity DataKi:  9nMAssay Description:Inhibition of full length wild-type LRRK2 (unknown origin) using biotinylated ezrin/radaxin/meosin peptide as substrate measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50426403(CHEMBL2326726)
Affinity DataIC50: 28nMAssay Description:Inhibition of LRRK2 (unknown origin) autophosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50426403(CHEMBL2326726)
Affinity DataIC50: 1.00E+4nMAssay Description:Reversible inhibition of CYP1A2 (unknown origin) using phenacetin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed