BDBM50426477 CHEMBL2322702

SMILES C[C@@H]1CN(CCN1S(=O)(=O)c1cn(C)c(n1)C(C)(O)C(F)(F)F)c1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=KEQKJYAUPNCMBM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50426477   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426477(CHEMBL2322702)
Affinity DataIC50: 43nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426477(CHEMBL2322702)
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426477(CHEMBL2322702)
Affinity DataIC50: 77nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed