BDBM50426740 CHEMBL2322140

SMILES C1CCC(CC1)N1CCCc2cnc3[nH]ccc3c12

InChI Key InChIKey=FIOJSASVXZIWJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50426740   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426740(CHEMBL2322140)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FLT3 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1000 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426740(CHEMBL2322140)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Aurora 1 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426740(CHEMBL2322140)
Affinity DataIC50: 530nMAssay Description:Inhibition of TYK2 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed