BDBM50427623 CHEMBL2323476

SMILES Cc1c(CC(O)=O)c2cc(F)ccc2n1C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=UEEDYBNIUXWFAP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50427623   

TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50427623(CHEMBL2323476)
Affinity DataIC50: 90nMAssay Description:Inhibition of wild type mouse COX2 by discontinuous radioactive TLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50427623(CHEMBL2323476)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant AKR1C3-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50427623(CHEMBL2323476)
Affinity DataIC50: 490nMAssay Description:Inhibition of ovine COX1 by discontinuous radioactive TLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50427623(CHEMBL2323476)
Affinity DataIC50: 6.19E+3nMAssay Description:Inhibition of human recombinant AKR1C2-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed