BDBM50427696 CHEMBL2324201

SMILES NC(N)=NCCC[C@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)[C@H](O)C(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(N)=O

InChI Key InChIKey=BHQDUEIUHBHLON-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50427696   

TargetMatrilysin(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427696(CHEMBL2324201)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of MMP7 (unknown origin)-mediated omniMMP degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427696(CHEMBL2324201)
Affinity DataKi:  26nMAssay Description:Inhibition of human recombinant IDE-mediated FRET1 degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427696(CHEMBL2324201)
Affinity DataKi:  70nMAssay Description:Inhibition of human recombinant IDE-mediated fluorescein-Abeta-(1-40)-Lys-biotin degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50427696(CHEMBL2324201)
Affinity DataKi:  275nMAssay Description:Inhibition of human recombinant IDE-mediated insulin degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed