BDBM50428329 CHEMBL2338390

SMILES CO[C@@H]1COCC[C@@H]1NC1CCN(CC1)C(=O)c1nc(nc(N2CCc3cc(ccc3C2)C(F)(F)F)c1C)C(F)(F)F

InChI Key InChIKey=HKIFMAJLMSGIOP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428329   

TargetC-C chemokine receptor type 2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50428329(CHEMBL2338390)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human THP1 cell membranes after 8 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50428329(CHEMBL2338390)
Affinity DataKi:  150nMAssay Description:Displacement of [125I]RANTES from human CCR5 expressed in CHO cell membranes coexpressing Gal6 after 6 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed