BDBM50428936 CHEMBL2332748

SMILES CCn1c(C)c(-c2ccc(C[C@H](NC(=O)c3c(C)cccc3Cl)C(O)=O)cc2)c(=O)n(CC)c1=O

InChI Key InChIKey=IECKVUVUZIOYDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428936   

TargetIntegrin alpha-4/beta-7(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50428936(CHEMBL2332748)
Affinity DataIC50: 164nMAssay Description:Inhibition of human MAdCAM1 binding to integrin alpha4beta7 receptor in human RPMI 8866 cells labeled with Calcein AMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50428936(CHEMBL2332748)
Affinity DataIC50: 296nMAssay Description:Inhibition of human VCAM1 binding to integrin alpha4beta1 receptor in human Ramos cells labeled with Calcein AMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed