BDBM50429009 CHEMBL2334100

SMILES Cc1c(oc2ccc(cc12)-c1ccccc1)C(=O)Nc1ccc(nc1)N1CCC(COc2cccc(c2)C(O)=O)CC1

InChI Key InChIKey=MXPRNVBVWZYUBT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50429009   

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50429009(CHEMBL2334100)
Affinity DataIC50: 52nMAssay Description:Inhibition of human DGAT1 expressed in Sf9 cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-Co A substrates incubated for 2 hrs by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50429009(CHEMBL2334100)
Affinity DataIC50: 800nMAssay Description:Inhibition of human ACAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50429009(CHEMBL2334100)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human DGAT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50429009(CHEMBL2334100)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human ACAT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed