BDBM50429422 CHEMBL2338563

SMILES Clc1cccc(c1)C(=O)NC1CCCC(C1)NC(=O)c1ncccc1C#N

InChI Key InChIKey=SFPHLFHZUAYDLI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50429422   

TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50429422(CHEMBL2338563)
Affinity DataIC50: 671nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50429422(CHEMBL2338563)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed