BDBM50429650 CHEMBL2334981

SMILES CC(C)c1cccc(n1)-c1c(NC(=O)[C@@H]2C[C@H]2C)snc1-c1ccc2nn(C)cc2c1

InChI Key InChIKey=FYGXJVFGWUEFMS-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50429650   

TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50429650(CHEMBL2334981)
Affinity DataIC50: 644nMAssay Description:Negative allosteric modulation of human recombinant mGlu1 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50429650(CHEMBL2334981)
Affinity DataIC50: 19nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50429650(CHEMBL2334981)
Affinity DataIC50: 167nMAssay Description:Negative allosteric modulation of rat mGlu5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50429650(CHEMBL2334981)
Affinity DataKi:  3.16E+3nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed