BDBM50430146 CHEMBL2338265

SMILES CC1CN([C@H]2C3CC4CC2C[C@@](O)(C4)C3)C(=O)c2cnn(c2C1)-c1ccccc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430146   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430146(CHEMBL2338265)
Affinity DataIC50: 25nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430146(CHEMBL2338265)
Affinity DataIC50: 72nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed