BDBM50430728 CHEMBL2333928

SMILES C[C@H](Cc1ccc(OCCCCCNc2c3CCCCc3nc3cc(Cl)ccc23)cc1)N(C)CC#C

InChI Key InChIKey=NABJRKRPLBDFTB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50430728   

TargetCholinesterase(Horse)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50430728(CHEMBL2333928)
Affinity DataIC50: 19nMAssay Description:Inhibition of horse serum BChE using butyrylthiocholine chloride as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50430728(CHEMBL2333928)
Affinity DataIC50: 82nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50430728(CHEMBL2333928)
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine substrate preincubated for 15 mins before substrate addition measured after 20 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50430728(CHEMBL2333928)
Affinity DataIC50: 6.21E+3nMAssay Description:Inhibition of recombinant human MAO-B using p-benzylamine substrate preincubated for 15 mins before substrate addition measured after 20 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed