BDBM50430959 CHEMBL2337401

SMILES Cc1c(CCOCCO[N+]([O-])=O)cc(-c2ccc(cc2)S(C)(=O)=O)n1-c1cccc(F)c1

InChI Key InChIKey=IPXDLSQHFQLZKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430959   

TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430959(CHEMBL2337401)
Affinity DataIC50: 27nMAssay Description:Inhibition of Escherichia coli lipopolysaccharide-induced COX2 activity in mouse J774 cells assessed as decrease in PGE2 levels after 24 hrs by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430959(CHEMBL2337401)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of arachidonic acid-induced COX1 activity in mouse J774 cells assessed as decrease in PGE2 levels incubated for 15 mins prior to arachidon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed