BDBM50431018 CHEMBL2338326

SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1ccc2ccccc2c1

InChI Key InChIKey=NTFMWXJMENAQDA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50431018   

TargetProlyl hydroxylase EGLN3(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50431018(CHEMBL2338326)
Affinity DataIC50: 17nMAssay Description:Inhibition of full length human recombinant EGLN-3 using DLDLEALAPYIPADDDFQL as substrate after 20 mins by mass spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50431018(CHEMBL2338326)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant EGLN-1 using DLDLEALAPYIPADDDFQL as substrate after 20 mins by mass spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431018(CHEMBL2338326)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed