BDBM50431076 CHEMBL2338788::US10202399, Example 53::US9212147, 53

SMILES Oc1cc(CCCc2ccccc2)n[nH]c1=O

InChI Key InChIKey=AYKHZIXAQMKCHB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50431076   

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431076(CHEMBL2338788 | US9212147, 53 | US10202399, Exampl...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431076(CHEMBL2338788 | US9212147, 53 | US10202399, Exampl...)
Affinity DataIC50: 233nMAssay Description:Inhibition of human full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431076(CHEMBL2338788 | US9212147, 53 | US10202399, Exampl...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431076(CHEMBL2338788 | US9212147, 53 | US10202399, Exampl...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431076(CHEMBL2338788 | US9212147, 53 | US10202399, Exampl...)
Affinity DataIC50: 426nMAssay Description:Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431076(CHEMBL2338788 | US9212147, 53 | US10202399, Exampl...)
Affinity DataIC50: 13nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent