BDBM50432421 CHEMBL2349152

SMILES COc1ccc(cc1)C(=O)CCc1ccc(cc1)C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nccs1

InChI Key InChIKey=QGIYLBVQZALCCL-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50432421   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50432421(CHEMBL2349152)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human PTP1B assessed as inhibition of hydrolysis of pNPP by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50432421(CHEMBL2349152)
Affinity DataKi:  5.80E+3nMAssay Description:Non-competitive inhibition of recombinant human PTP1B assessed as inhibition of hydrolysis of pNPP by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50432421(CHEMBL2349152)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50432421(CHEMBL2349152)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human VHRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50432421(CHEMBL2349152)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LYP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50432421(CHEMBL2349152)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of TC-PTP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed