BDBM50432703 CHEMBL2348217

SMILES CCOCCOc1ccc(OCC(O)CNCCNC(=O)Nc2ccc(O)cc2)cc1

InChI Key InChIKey=LZAHCRHPGUIOBW-UHFFFAOYSA-N

Data  4 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50432703   

TargetBeta-1 adrenergic receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432703(CHEMBL2348217)
Affinity DataEC50:  23nMAssay Description:Partial agonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432703(CHEMBL2348217)
Affinity DataKd:  27nMAssay Description:Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432703(CHEMBL2348217)
Affinity DataKd:  91nMAssay Description:Displacement of [3H]-CGP12177 from human beta1 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432703(CHEMBL2348217)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432703(CHEMBL2348217)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432703(CHEMBL2348217)
Affinity DataKd: >1.00E+4nMAssay Description:Antagonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432703(CHEMBL2348217)
Affinity DataKd: >1.00E+4nMAssay Description:Antagonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed