BDBM50433613 CHEMBL1080151

SMILES C[C@H](Nc1nc(Nc2ncc(C)s2)c(F)c(n1)N1CCOCC1)c1ncc(F)cn1

InChI Key InChIKey=NOLJFJNOWXBGKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433613   

TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433613(CHEMBL1080151)
Affinity DataIC50: 25nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433613(CHEMBL1080151)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed