BDBM50433614 CHEMBL2381977

SMILES C[C@H](Nc1nc(Nc2ncc(C)s2)nc(N2CCOCC2)c1F)c1ncc(F)cn1

InChI Key InChIKey=BGCLPDIMXFCTKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433614   

TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433614(CHEMBL2381977)
Affinity DataIC50: 20nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433614(CHEMBL2381977)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed