BDBM50434244 CHEMBL2385908

SMILES CCOC(=O)C1C(NC(=O)N=C1C)c1ccc(OCc2ccccc2)c(OC)c1

InChI Key InChIKey=PFDMEJDKXUKJBA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434244   

TargetNuclear receptor ROR-alpha(Human)
Genfit

Curated by ChEMBL
LigandPNGBDBM50434244(CHEMBL2385908)
Affinity DataEC50:  8.90E+3nMAssay Description:Partial agonist activity at GST-fussed RORalpha (unknown origin) assessed as recruitment of TIF2-BAP protein after overnight incubation by pull down ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50434244(CHEMBL2385908)
Affinity DataIC50: 2.09E+4nMAssay Description:Agonist activity at 6His-tagged human RORC LBD (262 to 507 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as inhibition of N-termi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed