BDBM50434422 CHEMBL2387570

SMILES CC(C)[C@H](C[C@H](O)[C@@H](N)CN1CC(=O)N(CC1(C)C)c1ccccc1Cl)C(=O)NC12CC3CC(CC(O)(C3)C1)C2

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434422   

TargetRenin(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50434422(CHEMBL2387570)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant renin using Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys (DABCYL)-Arg as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetRenin(Crab-eating macaque)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50434422(CHEMBL2387570)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of renin in cynomolgus monkey plasma after 1 hr by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed