BDBM50434450 CHEMBL2387542

SMILES COC(=O)C(C)(C)CNC(=O)[C@@H](C[C@H](O)[C@@H](N)CN1CC(=O)N(CC1(C)C)c1ccccc1Cl)C(C)C

InChI Key InChIKey=YVMULRMGHZWOMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434450   

TargetRenin(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50434450(CHEMBL2387542)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant renin using Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys (DABCYL)-Arg as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetRenin(Crab-eating macaque)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50434450(CHEMBL2387542)
Affinity DataIC50: 23nMAssay Description:Inhibition of renin in cynomolgus monkey plasma after 1 hr by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed