BDBM50435367 CHEMBL2391554::US11279687, Compound 114

SMILES O=C(NCc1ccc(cc1)S(=O)(=O)N1CCCCC1)NCc1cccnc1

InChI Key InChIKey=CSIOZEDWHIRRPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435367   

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50435367(CHEMBL2391554 | US11279687, Compound 114)
Affinity DataIC50: 17nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM50435367(CHEMBL2391554 | US11279687, Compound 114)
Affinity DataIC50: 19nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed