BDBM50435396 CHEMBL2391916

SMILES O=c1n(CCc2ccccc2)sc2ccccc12

InChI Key InChIKey=VUMUTUGUKRGYGW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50435396   

TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50435396(CHEMBL2391916)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50435396(CHEMBL2391916)
Affinity DataIC50: 605nMAssay Description:Inhibition of recombinant rat MGL C201A/C208A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50435396(CHEMBL2391916)
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant rat MGL C208A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50435396(CHEMBL2391916)
Affinity DataIC50: 9.38E+3nMAssay Description:Inhibition of FAAH in rat brain homogenates using [3H]anandamide as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50435396(CHEMBL2391916)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50435396(CHEMBL2391916)
Affinity DataIC50: 243nMAssay Description:Inhibition of recombinant rat MGL C201A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50435396(CHEMBL2391916)
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of mouse ABHD6 expressed in HEK293 cells using 2-AG as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed