BDBM50435519 CHEMBL2392493

SMILES CC1(CCN(CC1)S(C)(=O)=O)n1nnc2cnc3[nH]ccc3c12

InChI Key InChIKey=AATBKSLPLAFVJV-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50435519   

TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435519(CHEMBL2392493)
Affinity DataEC50:  220nMAssay Description:Inhibition of JAK1-mediated STAT3 phosphorylation in IL6-induced human TF1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435519(CHEMBL2392493)
Affinity DataKi:  7.90nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435519(CHEMBL2392493)
Affinity DataKi:  53nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435519(CHEMBL2392493)
Affinity DataKi:  369nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed