BDBM50435773 CHEMBL2393166

SMILES CC1CNCCN(C1)S(=O)(=O)c1ccc(NC(=O)NCc2cccnc2)cc1

InChI Key InChIKey=BPUAGRPBQYKIBQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435773   

TargetNicotinamide phosphoribosyltransferase(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50435773(CHEMBL2393166)
Affinity DataIC50: 100nMAssay Description:Inhibition of NAMPT (unknown origin) assessed as NAM conversion to NMN preincubated for 15 mins prior to substrate addition measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50435773(CHEMBL2393166)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed