BDBM50436434 CHEMBL2397138

SMILES CNC(=O)c1ccc(cc1)OC2CCC(CC2)NC(=O)Nc3ccc(cc3)OC(F)(F)F

InChI Key InChIKey=JNPWHXLRBKEIPP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50436434   

TargetBifunctional epoxide hydrolase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50436434(CHEMBL2397138)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50436434(CHEMBL2397138)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in baculovirus-infected High Five cells S9 fraction using CMNPC substrate by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50436434(CHEMBL2397138)
Affinity DataIC50: 170nMAssay Description:Inhibition of human FAAH expressed in baculovirus-infected High Five cells S9 fraction using OMP substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed