BDBM50438313 CHEMBL2408735

SMILES Cn1cc(c(n1)C#N)-c1cnc(N)c2oc(cc12)-c1csc2cnccc12

InChI Key InChIKey=TULIQLJVECRCBC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438313   

TargetMitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1(Human)
Osi Pharmaceuticals

Curated by ChEMBL

LigandBDBM50438313(CHEMBL2408735)Copy SMILESCopy InChI

Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
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TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL

LigandBDBM50438313(CHEMBL2408735)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL