BDBM50438424 CHEMBL2414139::US8637558, 17

SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCN2CCS(=O)(=O)CC2)c(Cl)c1

InChI Key InChIKey=SILNVQUZVJOYTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438424   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50438424(CHEMBL2414139 | US8637558, 17)
Affinity DataIC50: 223nMAssay Description:Inhibition of human GST-fused 15-PGDH expressed in Escherichia coli BL21 using PGE2 as substrate assessed as formation of NADH by fluorescence spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50438424(CHEMBL2414139 | US8637558, 17)
Affinity DataIC50: 308nMpH: 7.5Assay Description:Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent