BDBM50438460 CHEMBL2414617

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(s2)-c2ccc(F)nc2)c1

InChI Key InChIKey=WQWNUPFPUXHKAQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50438460   

TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50438460(CHEMBL2414617)
Affinity DataIC50: 2nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50438460(CHEMBL2414617)
Affinity DataIC50: 2nMAssay Description:Inhibition of human SGLT2 expressed in HEK293T cells using [14C] alpha-MDG as substrate incubated for 30 mins by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSodium/glucose cotransporter 1(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50438460(CHEMBL2414617)
Affinity DataIC50: 750nMAssay Description:Inhibition of human SGLT1 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed