BDBM50438996 CHEMBL2420681

SMILES COc1ccc2ccc(-c3cncc(OC)c3)c(Cl)c2c1

InChI Key InChIKey=VEDXLNFHAQEVMU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50438996   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50438996(CHEMBL2420681)
Affinity DataIC50: 24nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50438996(CHEMBL2420681)
Affinity DataIC50: 94nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using 1,2[3H]-progesterone as substrate in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50438996(CHEMBL2420681)
Affinity DataIC50: 447nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50438996(CHEMBL2420681)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP19 in human placental microsomes using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed