BDBM50439351 CHEMBL2420384

SMILES COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCc2ccccc2)c1

InChI Key InChIKey=ASZXUJWASJMAAI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439351   

TargetLeucyl-cystinyl aminopeptidase(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50439351(CHEMBL2420384)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant IRAP expressed in HeLa cells assessed as L-Leucine-7-amido-4-methyl coumarin hydrolysis to 7-amido-4-methyl coumarin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50439351(CHEMBL2420384)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus-infected Hi5 insect cells assessed as L-Arginyl-7-amido-4-methyl coumarin h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50439351(CHEMBL2420384)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of recombinant ERAP1 (unknown origin) expressed in baculovirus-infected Hi5 insect cells assessed as L-Leucine-7-amido-4-methyl coumarin h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed