BDBM50439434 CHEMBL2420701

SMILES Cn1cc(c(n1)-c1ccc(F)cc1)-c1ccnc(CO)c1

InChI Key InChIKey=HRZWHDGMDXCUTR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439434   

TargetCasein kinase I isoform delta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439434(CHEMBL2420701)
Affinity DataIC50: 237nMAssay Description:Inhibition of human CK1 delta transfected in african green monkey cos7 cells after overnight incubation by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCasein kinase I isoform epsilon(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439434(CHEMBL2420701)
Affinity DataIC50: 82nMAssay Description:Inhibition of CK1 epsilon (unknown origin) using PLSRTLpSVASLPGL as substrate after 85 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439434(CHEMBL2420701)
Affinity DataIC50: 14nMAssay Description:Inhibition of CK1 delta (unknown origin) using PLSRTLpSVASLPGL as substrate after 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed