BDBM50439612 CHEMBL2419296

SMILES CC1N(C2CC2)C(=O)C(=C1c1ccc2OCC(=O)Nc2c1)c1ccc(F)cc1

InChI Key InChIKey=OHUSXUGFNIRYCY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50439612   

TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439612(CHEMBL2419296)
Affinity DataIC50: 68nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439612(CHEMBL2419296)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439612(CHEMBL2419296)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439612(CHEMBL2419296)
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed