BDBM50439672 CHEMBL2417783

SMILES Cc1onc(c1C(=O)NCCCCCNC(=O)CS)-c1ccccc1

InChI Key InChIKey=WWLIISZAGFGMDE-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50439672   

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant full length HDAC6 expressed in baculovirus infected sf9 insect cells using p53 fluorogenic peptide (379 to 382 residu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human recombinant full length HDAC2 expressed in baculovirus infected sf9 insect cells using p53 fluorogenic peptide (379 to 382 residu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human recombinant full length HDAC1 expressed in baculovirus infected sf9 insect cells using p53 fluorogenic peptide (379 to 382 residu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human full length recombinant HDAC1 expressed in baculovirus infected Sf9 cells using RHKKAc as substrate preincubated for 5 to 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human full length recombinant HDAC2 expressed in baculovirus infected Sf9 cells using RHKKAc as substrate preincubated for 5 to 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Scripps Research

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant HDAC3/NCOR2 expressed in baculovirus infected Sf9 cells using RHKKAc as substrate preincubated for 5 to 10 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 260nMAssay Description:Inhibition of human full length recombinant HDAC6 expressed in baculovirus infected Sf9 cells using RHKKAc as substrate preincubated for 5 to 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human full-length recombinant HDAC1 incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 260nMAssay Description:Inhibition of human full-length recombinant HDAC6 incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed